Dr James Pritchett MRSB FHEA

Pilkington, J.J., Wilkinson, F., Pritchett, J., Fullwood, C., Sheen, A. (2026) 'SRS353 - Can plasma procollagen levels predict incisional hernia recurrence following surgical repair?.' British Journal of Surgery, 113(Supplement_2)

Pilkington, J.J., Pritchett, J., Fullwood, C., Herring, A., Wilkinson, F.L., Sheen, A.J. (2024) 'TACKoMesh – A randomised controlled trial comparing absorbable versus non-absorbable tack fixation in laparoscopic IPOM + repair of primary incisional hernia using post-operative pain and quality of life - Reliatack™ versus Protack™.' Hernia, 28(5) pp. 1879-1888.

Jokl, E., Mullan, A.F., Simpson, K., Birchall, L., Pearmain, L., Martin, K., Pritchett, J., Raza, S., Shah, R., Hodson, N.W., Williams, C.J., Camacho, E., Zeef, L., Donaldson, I., Athwal, V.S., Hanley, N.A., Piper Hanley, K. (2023) 'PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis.' Cell Reports, 42(11)

Jokl, E., Llewellyn, J., Simpson, K., Adegboye, O., Pritchett, J., Zeef, L., Donaldson, I., Athwal, V.S., Purssell, H., Street, O., Bennett, L., Guha, I.N., Hanley, N.A., Meng, Q.J., Piper Hanley, K. (2023) 'Circadian disruption primes myofibroblasts for accelerated activation as a mechanism underpinning fibrotic progression in non-alcoholic fatty liver disease.' Cells, 12(12) pp. 1582-1582.

Jokl, E., Llewelyn, J., Simpson, K., Adegboye, O., Pritchett, J., Zeef, L., Meng, Q.J., Hanley, K.P. (2023) 'CLOCKΔ19 circadian disruption primes myofibroblasts for accelerated activation and fibrotic progression.' Journal of Hepatology, 78pp. S76-S77.

Verran, J., Illingworth, S., Pritchett, J., Redfern, J. (2023) 'Co-development, co-delivery, and evaluation of a Medical Writing module at master’s level.' Medical Writing, 32(1) pp. 92-98.

Pilkington, J., Wilkinson, F., Pritchett, J., Fullwood, C., Sheen, A.J. (2022) 'OC-088 CAN PROCOLLAGEN I AND PROCOLLAGEN III SERVE AS PREDICTIVE BIOMARKERS FOR INCISIONAL HERNIA RECURRENCE?.' British Journal of Surgery, 109(Supplement_7)

Pilkington, J., Wilkinson, F., Pritchett, J., Fullwood, C., Sheen, A.J. (2022) 'OC-087 PAIN AND INFLAMMATORY SIGNALLING IN TACKOMESH TRIAL PARTICIPANTS FOLLOWING ELECTIVE LAPAROSCOPIC INCISIONAL HERNIA REPAIR WITH INTRAPERITONEAL ONLAY MESH (IPOM) AND SPIRAL-TACK MESH FIXATION.' British Journal of Surgery, 109(Supplement_7)

Pilkington, J., Wilkinson, F., Pritchett, J., Fullwood, C., Sheen, A.J. (2022) 'OC-086 COMPARISON OF MESH-FIXATION TECHNIQUES IN LAPAROSCOPIC REPAIR OF INCISIONAL HERNIA, RELIATACK™ V PROTACK™ (TACKOMESH) NCT 03434301.' British Journal of Surgery, 109(Supplement_7)

Silvagnoli, L.M., Shepherd, C., Pritchett, J., Gardner, J. (2022) 'Optimizing Readability and Format of Plain Language Summaries for Medical Research Articles: Cross-sectional Survey Study.' Journal of Medical Internet Research, 24(1)

Pilkington, J.J., Davies, T.W., Schaff, O., Alexander, M.Y., Pritchett, J., Wilkinson, F.L., Sheen, A.J. (2021) 'Systemic biomarkers currently implicated in the formation of abdominal wall hernia: A systematic review of the literature.' American Journal of Surgery, 222(1) pp. 56-66.

Raza, S., Jokl, E., Pritchett, J., Martin, K., Su, K., Simpson, K., Birchall, L., Mullan, A.F., Athwal, V.S., Doherty, D.T., Zeef, L., Henderson, N.C., Kalra, P.A., Hanley, N.A., Hanley, K.P. (2021) 'SOX9 is required for kidney fibrosis and activates NAV3 to drive renal myofibroblast function.' Science Signaling, 14(672)

Redfern, J., Ratova, M., Dean, A.P., Pritchett, J., Grao, M., Verran, J., Kelly, P. (2020) 'Visible light photocatalytic bismuth oxide coatings are effective at suppressing aquatic cyanobacteria and degrading free-floating genomic DNA.' Journal of Environmental Sciences, 104pp. 128-136.

Abdelmottaleb, D., Hanley, K.P., Pritchett, J. (2020) 'Enigma proteins control YAP1 related mechano-transduction in hepatic stellate cells.' Journal of Hepatology, 73pp. S511-S511.

Soydemir, S., Comella, O., Abdelmottaleb, D., Pritchett, J. (2019) 'Does Mechanocrine Signalling by Liver Sinusoidal Endothelial Cells Offer New Opportunities for the Development of Anti-fibrotics?.' Frontiers in Medicine, 6

Scott, J., Jokl, E., Pritchett, J., Piper-Hanley, K., Barry, P., Athwal, V., Jones, A. (2019) 'P309 FibroScan improves diagnosis of Cystic Fibrosis-Related Liver Disease.' Journal of Cystic Fibrosis, 18pp. S144-S144.

Athwal, V.S., Pritchett, J., Martin, K., Llewellyn, J., Scott, J., Harvey, E., Zaitoun, A.M., Mullan, A.F., Zeef, L.A.H., Friedman, S.L., Irving, W.L., Hanley, N.A., Guha, I.N., Piper Hanley, K. (2018) 'SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis.' Scientific Reports, 8

Malic, S., Rai, S., Redfern, J., Pritchett, J., Liauw, C., Verran, J., Tosheva, L. (2018) 'Zeolite-embedded silver extends antimicrobial activity of dental acrylics.' Colloids and Surfaces B: Biointerfaces, 173pp. 52-57.

Athwal, V.S., Pritchett, J., Llewellyn, J., Martin, K., Camacho, E., Raza, S.M.A., Phythian‐Adams, A., Birchall, L.J., Mullan, A.F., Su, K., Pearmain, L., Dolman, G., Zaitoun, A.M., Friedman, S.L., MacDonald, A., Irving, W.L., Guha, I.N., Hanley, N.A., Piper Hanley, K. (2017) 'SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.' EMBO Molecular Medicine, 9(12) pp. 1696-1710.

Martin, K., Pritchett, J., Llewellyn, J., Mullan, A.F., Athwal, V.S., Dobie, R., Harvey, E., Zeef, L., Farrow, S., Streuli, C., Henderson, N.C., Friedman, S.L., Hanley, N.A., Piper Hanley, K. (2016) 'PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.' Nature Communications, 7

Pritchett, J., Athwal, V.S., Harvey, E., Martin, K., Llewellyn, J., Ireland, P., Nicolaides, A., Humphries, M.J., Bobola, N., Hanley, N.A., Piper Hanley, K. (2014) 'Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells..' PloS one, 9(6)

Pritchett, J., Harvey, E., Athwal, V., Berry, A., Rowe, C., Oakley, F., Moles, A., Mann, D.A., Bobola, N., Sharrocks, A.D., Thomson, B.J., Zaitoun, A.M., Irving, W.L., Guha, I.N., Hanley, N.A., Hanley, K.P. (2012) 'Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.' Hepatology, 56(3) pp. 1108-1116.

Pritchett, J., Athwal, V., Roberts, N., Hanley, N.A., Hanley, K.P. (2011) 'Understanding the role of SOX9 in acquired diseases: Lessons from development.' Trends in Molecular Medicine, 17(3) pp. 166-174.

Clarke, C.J., Forman, S., Pritchett, J., Ohanian, V., Ohanian, J. (2008) 'Phospholipase C-δ1 modulates sustained contraction of rat mesenteric small arteries in response to noradrenaline, but not endothelin-1.' American Journal of Physiology Heart and Circulatory Physiology, 295(2) pp. H826-H834.

Liapi, A., Pritchett, J., Jones, O., Fujii, N., Parnavelas, J.G., Nadarajah, B. (2007) 'Stromal-derived factor 1 signalling regulates radial and tangential migration in the developing cerebral cortex.' Developmental Neuroscience, 30(1-3) pp. 117-131.

Pritchett, J., Wright, C., Zeef, L., Nadarajah, B. (2007) 'Stromal derived factor-1 exerts differential regulation on distinct cortical cell populations in vitro.' BMC Developmental Biology, 7

Parkin, S.L., Pritchett, J.P., Grimsditch, D.C., Bruckdorfer, K.R., Sahota, P.K., Lloyd, A., Overend, P., Benson, G.M. (2004) 'Circulating levels of the chemokines JE and KC in female C3H apolipoprotein-E-deficient and C57BL apolipoprotein-E-deficient mice as potential markers of atherosclerosis development.' Biochemical Society Transactions, 32(1) pp. 128-130.

Mcdowall, C., Shalamanova, L., Wilkinson, F., Pritchett, J., White, S., Kalra, P.A. (2024) '#3004 Serum miRNAs as novel biomarkers and modulators of rapidly progressing chronic kidney disease in patients with diabetes.' 39. Oxford University Press (OUP),

Abdelmottaleb, D., Hanley, K.P., Pritchett, J. (2020) 'P2 PDLIM5 in hepatic stellate cells is upstream of pro-fibrotic YAP1 mechano-transduction.' In BASL Abstracts, 21–23 September, 2020. BMJ Publishing Group Ltd and British Society of Gastroenterology, pp. A7.2-A8.

Gardner, J., Silvagnoli, L.M.I., Shepherd, C., Pritchett, J. (2019) 'Evaluation of plain-language summaries (PLSs): optimizing readability and format.' 35. TAYLOR & FRANCIS LTD, pp. 36-36.

Athwal, V., Pritchett, J., Scott, J., Martin, K., Irving, W., Guha, N., Hanley, N., Hanley, K.P. (2019) 'SOX9 regulates extracellular matrix proteins in liver fibrosis that correlate with severity of fibrosis.' In International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL). 70. Vienna, AUSTRIA, 10/4/2019 - 14/4/2019. ELSEVIER, pp. E57-E57.

Scott, J., Jokl, E., Pritchett, J., Jones, A., Barry, P., Hanley, K.P., Athwal, V. (2019) 'Fibroscan improves diagnosis of cystic fibrosis related liver disease.' In International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL). 70. Vienna, AUSTRIA, 10/4/2019 - 14/4/2019. ELSEVIER, pp. E122-E123.

Chauhan, A., Lalor, T., Watson, S., Adams, D., Farrah, T.E., Anand, A., Kimmitt, R., Mills, N.L., Webb, D.J., Dhaun, N., Kalla, R., Adams, A., Vatn, S., Bonfliglio, F., Nimmo, E., Kennedy, N., Ventham, N., Vatn, M., Ricanek, P., Halfvarson, J., Soderhollm, J., Pierik, M., Torkvist, L., Gomollon, F., Gut, I., Jahnsen, J., Satsangi, J., Body, R., Almashali, M., McDowell, G., Taylor, P., Lacey, A., Rees, A., Dayan, C., Lazarus, J., Nelson, S., Okosieme, O., Corcoran, D., Young, R., Ciadella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K., Berry, C., Parks, T., Auckland, K., Mentzer, A.J., Kado, J., Mirabel, M.M., Kauwe, J.K., Robson, K.J., Mittal, B., Steer, A.C., Hill, A.V.S., Akbar, M., Forrester, M., Virlan, A.T., Gilmour, A., Wallace, C., Paterson, C., Reid, D., Siebert, S., Porter, D., Liversidge, J., McInnes, I., Goodyear, C., Athwal, V., Pritchett, J., Zaitoun, A., Irving, W., Guha, I.N., Hanley, N.A., Hanley, K.P., Briggs, T., Reynolds, J., Rice, G., Bondet, V., Bruce, E., Crow, Y., Duffy, D., Parker, B., Bruce, I., Martin, K., Aoibheann Mullan, M., Llewellyn, J., Zeef, L., Farrow, S. (2018) 'Scientific Business Abstracts of the 112th Annual Meeting of the Association of Physicians of Great Britain and Ireland.' 111. pp. 920-924.

Chauhan, A., Lalor, T., Watson, S., Adams, D., Farrah, T.E., Anand, A., Kimmitt, R., Mills, N.L., Webb, D.J., Dhaun, N., Kalla, R., Adams, A., Vatn, S., Bonfliglio, F., Nimmo, E., Kennedy, N., Ventham, N., Vatn, M., Ricanek, P., Halfvarson, J., Soderhollm, J., Pierik, M., Torkvist, L., Gomollon, F., Gut, I., Jahnsen, J., Satsangi, J., Body, R., Almashali, M., McDowell, G., Taylor, P., Lacey, A., Rees, A., Dayan, C., Lazarus, J., Nelson, S., Okosieme, O., Corcoran, D., Young, R., Ciadella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K., Berry, C., Parks, T., Auckland, K., Mentzer, A.J., Kado, J., Mirabel, M.M., Kauwe, J.K., Robson, K.J., Mittal, B., Steer, A.C., Hill, A.V.S., Akbar, M., Forrester, M., Virlan, A.T., Gilmour, A., Wallace, C., Paterson, C., Reid, D., Siebert, S., Porter, D., Liversidge, J., McInnes, I., Goodyear, C., Athwal, V., Pritchett, J., Zaitoun, A., Irving, W., Guha, I.N., Hanley, N.A., Hanley, K.P., Briggs, T., Reynolds, J., Rice, G., Bondet, V., Bruce, E., Crow, Y., Duffy, D., Parker, B., Bruce, I., Martin, K., Pritchett, J., Aoibheann Mullan, M., Llewellyn, J., Athwal, V., Zeef, L., Farrow, S., Streuli, C., Henderson, N., Friedman, S., Hanley, N., Hanley, K.P. (2018) 'Scientific Business Abstracts of the 112th Annual Meeting of the Association of Physicians of Great Britain and Ireland..' 111. pp. 920-924.

Clausi, V., Shepherd, C., Gardner, J., Pritchett, J., Berrie, A. (2018) 'Do corresponding authors value the support of professional medical writers?.' 34. TAYLOR & FRANCIS LTD, pp. 33-33.

Pritchett, J., Llewellyn, J., Athwal, V.S., Martin, K., Harvey, E., Friedman, S.L., Hanley, N., Hanley, K.P. (2017) 'YAP Regulated SOX9 Expression Promotes Liver Fibrosis..' In 68th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting. 66. Washington, DC, 20/10/2017 - 24/10/2017. WILEY, pp. 209A-210A.

Athwal, V.S., Pritchett, J., Zaitoun, A., Irving, W., Guha, I.N., Hanley, N., Hanley, K.P. (2017) 'SOX9 predicts progression of liver fibrosis in patients with chronic hepatitis C.' In 68th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting. 66. Washington, DC, 20/10/2017 - 24/10/2017. WILEY, pp. 239A-239A.

Martin, K., Pritchett, J., Harvey, E., Athwal, V., Llewellyn, J., Streuli, C., Zeef, L., Hanley, N., Hanley, K.P. (2014) 'INTEGRIN beta 1 REGULATES HEPATIC STELLATE CELL ACTIVATION VIA THE ACTIN MYOSIN CYTOSKELETON.' In 49th Annual International Liver Congress of the European-Association-for-the-Study-of-the-Liver. 60. London, ENGLAND, 9/4/2014 - 13/4/2014. ELSEVIER SCIENCE BV, pp. S276-S276.

Pritchett, J.P., Martin, K., Llewellyn, J., Henderson, D., Athwal, V., Hanley, N., Piper Hanley, K. (2014) 'P617 MECHANOSENSITIVE SIGNALLING VIA Yap/Taz DURING HEPATIC STELLATE CELL ACTIVATION.' 60. Elsevier BV, pp. S274-S275.

Pritchett, J.P., Martin, K., Llewellyn, J., Henderson, D., Athwal, V., Hanley, N., Hanley, K.P. (2014) 'MECHANOSENSITIVE SIGNALLING VIA Yap/Taz DURING HEPATIC STELLATE CELL ACTIVATION.' In 49th Annual International Liver Congress of the European-Association-for-the-Study-of-the-Liver. 60. London, ENGLAND, 9/4/2014 - 13/4/2014. ELSEVIER SCIENCE BV, pp. S274-S275.

Martin, K., Pritchett, J., Harvey, E., Athwal, V., Llewellyn, J., Streuli, C., Zeef, L., Hanley, N., Piper Hanley, K. (2014) 'P621 INTEGREN β1 REGULATES HEPATIC STELLATE CELL ACTIVATION VIA THE ACTIN MYOSIN CYTOSKELETON.' 60. Elsevier BV, pp. S276-S276.

Martin, K., Pritchett, J., Harvey, E., Athwal, V., Streuli, C., Hanley, N., Piper Hanley, K. (2013) '1123 UNDERSTANDING INTEGRIN SIGNALLING DURING LIVER FIBROSIS PROVIDES INSIGHT INTO THEIR MODULATION AS A THERAPEUTIC STRATEGY TO TREAT THE DISEASE.' 58. Elsevier BV, pp. S458-S458.

Martin, K., Pritchett, J., Harvey, E., Athwal, V., Streuli, C., Hanley, N., Hanley, K.P. (2013) 'UNDERSTANDING INTEGRIN SIGNALLING DURING LIVER FIBROSIS PROVIDES INSIGHT INTO THEIR MODULATION AS A THERAPEUTIC STRATEGY TO TREAT THE DISEASE.' In International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL). 58. Amsterdam, NETHERLANDS, 24/4/2013 - 28/4/2013. ELSEVIER SCIENCE BV, pp. S458-S458.

Pritchett, J., Athwal, V., Harvey, E., Martin, K., Ireland, P., Nicolaides, A.T., Irving, W., Guha, I.N., Hanley, N., Hanley, K.P. (2012) 'Epimorphin signaling is associated with a quiescent-like HSC phenotype with implications for non invasive assay development in liver fibrosis.' In 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD). 56. Boston, MA, 9/11/2012 - 13/11/2012. WILEY-BLACKWELL, pp. 775A-775A.

Athwal, V., Pritchett, J., Harvey, E., Ireland, P., Martin, K., Dolman, G.E., Irving, W., Guha, I.N., Hanley, N., Hanley, K.P. (2012) 'Identification of SOX9 extracellular matrix targets in liver fibrosis provides insight into novel biomarkers of disease.' In 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD). 56. Boston, MA, 9/11/2012 - 13/11/2012. WILEY-BLACKWELL, pp. 262A-262A.

Pritchett, J., Athwal, V.S., Harvey, E., Oakley, F., Mann, D.A., Hanley, N., Piper-Hanley, K. (2010) 'IDENTIFICATION OF SOX9 AS A NOVEL MECHANISM TO EXPLAIN ASPECTS OF LIVER FIBROSIS.' In Annual General Meeting of the British-Society-of-Gastroenterology. 59. Liverpool, ENGLAND, 22/3/2010 - 25/3/2010. B M J PUBLISHING GROUP, pp. A12-A12.

Pritchett, J., Athwal, V., Harvey, E., Oakley, F., Mann, D., Hanley, N., Hanley, K.P. (2010) '104 SOX9 IS A CRITICAL REGULATOR OF EXTRACELLULAR MATRIX DEPOSITION DURING LIVER FIBROSIS.' 52. Elsevier BV, pp. S47-S47.

Pritchett, J., Athwal, V., Harvey, E., Oakley, F., Mann, D., Hanley, N., Hanley, K.P. (2010) 'SOX9 IS A CRITICAL REGULATOR OF EXTRACELLULAR MATRIX DEPOSITION DURING LIVER FIBROSIS.' In 45th Annual Meeting of the European-Association-for-the-Study-of-the-Liver. 52. Vienna, AUSTRIA, 14/4/2010 - 18/4/2010. ELSEVIER SCIENCE BV, pp. S47-S47.

Clarke, C.J., Forman, S., Pritchett, J., Ohanian, V., Ohanian, J. (2008) 'Phospholipase C alpha 1 modulates sustained contraction of rat mesenteric small arteries in response to noradrenaline, but not endothelin-1.' In 13th Annual Meeting of the European-Council-for-Cardiovascular-Research. 52. Nice, FRANCE, 10/10/2008 - 12/10/2008. LIPPINCOTT WILLIAMS & WILKINS, pp. 769-769.

Pritchett, J., Harris, S., Ohanian, V., Ohanian, J. (2008) 'Activation of phospholipase C and alpha 1D adrenoreceptors in rat mesenteric small arteries.' In 13th Annual Meeting of the European-Council-for-Cardiovascular-Research. 52. Nice, FRANCE, 10/10/2008 - 12/10/2008. LIPPINCOTT WILLIAMS & WILKINS, pp. 769-769.

Pritchett, J., Wright, C., Zeef, L., Nadarajah, B. (2006) 'Sdf-1/Cxcr4 signalling regulates proliferation during cortical development.' In 16th Biennial Meeting of the International-Society-for-Developmental-Neuroscience. 24. Banff, CANADA, 24/8/2006 - 28/8/2006. PERGAMON-ELSEVIER SCIENCE LTD, pp. 556-556.

Pritchett, J. (2002) 'My experience of work placement.' 30. Portland Press Ltd., pp. A26-A26.

Athwal, V.S., Pritchett, J., Martin, K., Llewellyn, J., Scott, J., Harvey, E., Zaitoun, A.M., Mullan, A.F., Zeef, L.A.H., Friedman, S.L., Irving, W.L., Hanley, N.A., Guha, I.N., Piper Hanley, K. (2019) Publisher Correction: SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis..