Dr Nina Dempsey-Hibbert

How I’ll teach you

Haematology and Transfusion Medicine - Haematopoiesis, Anaemias, Haematological Malignancies, Blood Grouping, Transfusion Reactions, Transfusion-Transmitted Infections

Other academic service (administration and management)

Programme Leader for BSc (Hons) Biomedical Science

Programme Leader for BSc Healthcare Science (Life Science)

Pathway Lead for MSc Clinical Science - Haematology and Transfusion

Pathway Lead for DClinSCi -Haematology and Transfusion

Research expertise

My research interests are broad, but centre around haematology, immunology and transfusion medicine.
My research applies directly to both the clinical setting and the industrial setting, with impact in
both sectors. Historically my research has focused on tumour cell biology, looking at the utility of signalling
pathway inhibitors to target the classic hallmarks of cancer. However, I have moved into the area of drug
repurposing, looking at anti-cancer and anti-platelet actions of novel compounds. My research has also
become more translational, having clear clinical impact; I have collaborated with clinicians and clinical
scientists in areas of transfusion-transmitted infection testing, blood conservation strategies and methods to
prevent transfusion-associated sepsis.

Academic collaborations

University of Auckland, New Zealand

University of Manchester, UK

University of Chester, UK

Royal Oldham Hospital, UK

Glan Clwyd Hospital, Wales, UK

Publications

• Journal articles

  L. Cappuyns, A. Tridente, Y. Stubbington, NC. Dempsey-Hibbert, K. Shokrollahi (2023). Review of Burn Resuscitation: Is Plasmalyte® a Comparable Alternative to Ringer's Lactate?. J Burn Care Res. 44(1), pp.81-86.

  N. Svenson, J. Bailey, S. Durairaj, N. Dempsey-Hibbert (2021). A simplified diagnostic pathway for the differential diagnosis of iron deficiency anaemia and anaemia of chronic disease. Int J Lab Hematol. 43(6), pp.1644-1652.

  J. Wilson-Nieuwenhuis, M. El-Mohtadi, K. Edwards, K. Whitehead, N. Dempsey-Hibbert (2021). Factors Involved in the onset of infection following bacterially contaminated platelet transfusions. Platelets. 32(7), pp.909-918.

  N. Jones, A. Tridente, NC. Dempsey-Hibbert (2021). Immature platelet indices alongside procalcitonin for sensitive and specific identification of bacteremia in the intensive care unit. Platelets. 32(7), pp.941-949.

  M. El Mohtadi, K. Whitehead, N. Dempsey-Hibbert, A. Belboul, J. Ashworth (2021). Estrogen deficiency – a central paradigm in age-related impaired healing?. EXCLI Journal. 20, pp.99-116.

  R. Grennhalgh, N. Dempsey-Hibbert, K. Vagg-Whitehead (2018). Antimicrobial Strategies and Economic Considerations for Polymeric Medical Implants. International Biodeterioration and Biodegradation. 136,

  MX. Fu, J. Ingram, C. Roberts, V. Nurmi, E. Watkins, et al. N. Dempsey, T. Golubchik, J. Breuer, S. Brailsford, WL. Irving, M. Andersson, P. Simmonds, H. Harvala. Blood donation screening for hepatitis B virus core antibodies: The importance of confirmatory testing and initial implication for rare blood donor groups. Vox Sanguinis.

  FJ. Saubade, S. Hughes, DJ. Wickens, J. Wilson-Nieuwenhuis, N. Dempsey-Hibbert, et al. GS. Crowther, G. West, P. Kelly, CE. Banks, KA. Whitehead. (2018). Effectiveness of titanium nitride silver coatings against Staphylococcus spp. in the presence of BSA and whole blood conditioning agents. International Biodeterioration and Biodegradation.

  SL. Lee, NC. Dempsey-Hibbert, D. Vimalachandran, TD. Wardle, PA. Sutton, et al. JHH. Williams. (2017). Re-examining HSPC1 inhibitors. Cell Stress and Chaperones. 22(2), pp.293-306.

  NC. Dempsey, HE. Ireland, CM. Smith, CF. Hoyle, JHH. Williams (2010). Heat Shock Protein translocation induced by membrane fluidization increases tumor-cell sensitivity to chemotherapeutic drugs. Cancer Lett. 296(2), pp.257-267.

  NC. Dempsey, F. Leoni, HE. Ireland, C. Hoyle, JHH. Williams (2010). Differential heat shock protein localization in chronic lymphocytic leukemia. J Leukoc Biol. 87(3), pp.467-476.

• Chapters in books

  SL. Lee, NC. Dempsey-Hibbert, D. Vimalachandran, TD. Wardle, PA. Sutton, et al. JHH. Williams. (2018). Primary Colorectal Cells Culture as a Translational Research Model. In: Methods in Molecular Biology. Springer New York, pp.97-105.

  SL. Lin, NC. Dempsey-Hibbert, D. Vimalachandran, TD. Wardle, P. Sutton, et al. JHH. Williams. (2015). Heat Shock Protein-Based Therapies. AAA. Asea, NN. Almasoud, S. Krishnan, P. Kaur. In: Heat Shock Protein-Based Therapies. Springer International Publishing,

  NC. Dempsey-Hibbert (2015). Analysis of Phosphorylated Protein Kinases in Endothelial Cells by Flow Cytometry. In: Handbook of Vascular Biology Techniques. Springer Netherlands, pp.465-474.

  N. C., C. Hoyle, J. H.H. (2014). Heat Shock Proteins in Chronic Lymphocytic Leukaemia. P. Oppezzo. In: Chronic Lymphocytic Leukemia. InTech,

  NC. Dempsey, F. Leoni, C. Hoyle, JHH. Williams (2011). Analysis of heat-shock protein localisation using flow cytometry. SK. Calderwood, TL. Prince. In: Methods in Molecular Biology. Humana Press, pp.155-164.

• Conferences

  NK. Binsaleh, A. Alqahtani, S. Jones, NC. Dempsey-Hibbert (2016). Platelet activation and aggregation is modulated by the Hodgkin lymphoma 'secretome'. In: BRITISH JOURNAL OF HAEMATOLOGY. British Soc Haematol, Glasgow, SCOTLAND, 18/4/2016. pp.70-70.

  A. Tridente, E. Smith, N. Dempsey-Hibbert, S. Bonney, P. Nee (2015). The implementation of a blood conservation strategy in critical care on transfusion requirements. In: Intensive Care Medicine Experimental. Berlin, 3/10/2015.

  SL. Lee, NC. Dempsey-Hibbert, P. Sutton, D. Vimalachandran, TD. Wardle, et al. J. Williams. (2014). PWE-018 Hspc1 Inhibitors Potentiate The Effect Of 5-fu In Primary Colorectal Cancer Cell Model. In: Gut. Manchester, ENGLAND, 16/6/2014. pp.A129.1-A129.

  NC. Dempsey, F. Leoni, JHH. Williams, C. Hoyle (2008). Heat Shock Protein Localisation in Chronic Lymphatic Leukaemia. In: BLOOD. San Francisco, CA, 6/12/2008. pp.725-726.