Dr Aneurin Kennerley

Fear, E.J., Torkelsen, F.H., Zamboni, E., Chen, K.J., Scott, M., Jeffery, G., Baseler, H., Kennerley, A.J. (2023) 'Use of 31P magnetisation transfer magnetic resonance spectroscopy to measure ATP changes after 670 nm transcranial photobiomodulation in older adults.' Aging Cell, 22(11)

Patel, P., Alghamdi, A., Shaw, G., Legge, C., Glover, M., Freeman, D., Hodgetts, H., Watson, E., Howard, F., Staniland, S., Kennerley, A.J., Wood, D., Moorehead, R., Hadfield, C., Rominiyi, O., Griffin, J., Collis, S.J., Hyde, S., Crossley, M., Paley, M., Muthana, M. (2023) 'Development of a Personalised Device for Systemic Magnetic Drug Targeting to Brain Tumours.' Nanotheranostics, 7(1) pp. 102-116.

James, A.D., Leslie, T.K., Kaggie, J.D., Wiggins, L., Patten, L., Murphy O’Duinn, J., Langer, S., Labarthe, M.C., Riemer, F., Baxter, G., McLean, M.A., Gilbert, F.J., Kennerley, A.J., Brackenbury, W.J. (2022) 'Sodium accumulation in breast cancer predicts malignancy and treatment response.' British Journal of Cancer, 127(2) pp. 337-349.

Fear, E.J., Kennerley, A.J., Rayner, P.J., Norcott, P., Roy, S.S., Duckett, S.B. (2022) 'SABRE hyperpolarized anticancer agents for use in ¹H MRI.' Magnetic Resonance in Medicine, 88(1) pp. 11-27.

Kennerley, A.J., Mitchell, D.A., Sebald, A., Watson, I. (2022) 'Real-time magnetic resonance imaging: mechanics of oral and facial function.' British Journal of Oral and Maxillofacial Surgery, 60(5) pp. 596-603.

Howard, F.H.N., Al-Janabi, H., Patel, P., Cox, K., Smith, E., Vadakekolathu, J., Pockley, A.G., Conner, J., Nohl, J.F., Allwood, D.A., Collado-Rojas, C., Kennerley, A., Staniland, S., Muthana, M. (2022) 'Nanobugs as Drugs: Bacterial Derived Nanomagnets Enhance Tumor Targeting and Oncolytic Activity of HSV-1 Virus.' Small, 18(13)

Rayner, P.J., Fekete, M., Gater, C.A., Ahwal, F., Turner, N., Kennerley, A.J., Duckett, S.B. (2022) 'Real-Time High-Sensitivity Reaction Monitoring of Important Nitrogen-Cycle Synthons by ¹⁵N Hyperpolarized Nuclear Magnetic Resonance.' Journal of the American Chemical Society,

Huber, L., Poser, B.A., Kaas, A.L., Fear, E.J., Dresbach, S., Berwick, J., Goebel, R., Turner, R., Kennerley, A.J. (2021) 'Validating layer-specific VASO across species.' NeuroImage, 237

Plesia, M., Stevens, O.A., Lloyd, G.R., Kendall, C.A., Coldicott, I., Kennerley, A.J., Miller, G., Shaw, P.J., Mead, R.J., Day, J.C.C., Alix, J.J.P. (2021) 'In Vivo Fiber Optic Raman Spectroscopy of Muscle in Preclinical Models of Amyotrophic Lateral Sclerosis and Duchenne Muscular Dystrophy.' ACS Chemical Neuroscience, 12(10) pp. 1768-1776.

Leslie, T.K., James, A.D., Zaccagna, F., Grist, J.T., Deen, S., Kennerley, A., Riemer, F., Kaggie, J.D., Gallagher, F.A., Gilbert, F.J., Brackenbury, W.J. (2019) 'Sodium homeostasis in the tumour microenvironment.' Biochimica et Biophysica Acta - Reviews on Cancer, 1872(2)

Iali, W., Roy, S.S., Tickner, B.J., Ahwal, F., Kennerley, A.J., Duckett, S.B. (2019) 'Hyperpolarising Pyruvate through Signal Amplification by Reversible Exchange (SABRE).' Angewandte Chemie, 131(30) pp. 10377-10381.

Iali, W., Roy, S.S., Tickner, B.J., Ahwal, F., Kennerley, A.J., Duckett, S.B. (2019) 'Hyperpolarising Pyruvate through Signal Amplification by Reversible Exchange (SABRE).' Angewandte Chemie - International Edition, 58(30) pp. 10271-10275.

Harris, S.S., Boorman, L.W., Das, D., Kennerley, A.J., Sharp, P.S., Martin, C., Redgrave, P., Schwartz, T.H., Berwick, J. (2018) 'Physiological and pathological brain activation in the anesthetized rat produces hemodynamic-dependent cortical temperature increases that can confound the BOLD fMRI signal.' Frontiers in Neuroscience, 12(AUG)

Harris, S.S., Boorman, L.W., Kennerley, A.J., Sharp, P.S., Martin, C., Redgrave, P., Schwartz, T.H., Berwick, J. (2018) 'Seizure epicenter depth and translaminar field potential synchrony underlie complex variations in tissue oxygenation during ictal initiation.' NeuroImage, 171pp. 165-175.

Hewitt, B.M., Yap, M.H., Hodson-Tole, E.F., Kennerley, A.J., Sharp, P.S., Grant, R.A. (2017) 'A novel automated rodent tracker (ART), demonstrated in a mouse model of amyotrophic lateral sclerosis..' Journal of Neuroscience Methods, 300pp. 147-156.

Bruyns-Haylett, M., Luo, J., Kennerley, A.J., Harris, S., Boorman, L., Milne, E., Vautrelle, N., Hayashi, Y., Whalley, B.J., Jones, M., Berwick, J., Riera, J., Zheng, Y. (2017) 'The neurogenesis of P1 and N1: A concurrent EEG/LFP study.' NeuroImage, 146pp. 575-588.

Dall'Ara, E., Boudiffa, M., Taylor, C., Schug, D., Fiegle, E., Kennerley, A.J., Damianou, C., Tozer, G.M., Kiessling, F., Müller, R. (2016) 'Longitudinal imaging of the ageing mouse.' Mechanisms of Ageing and Development, 160pp. 93-116.

Slack, R., Boorman, L., Patel, P., Harris, S., Bruyns-Haylett, M., Kennerley, A., Jones, M., Berwick, J. (2016) 'A novel method for classifying cortical state to identify the accompanying changes in cerebral hemodynamics.' Journal of Neuroscience Methods, 267pp. 21-34.

Kazan, S.M., Mohammadi, S., Callaghan, M.F., Flandin, G., Huber, L., Leech, R., Kennerley, A., Windischberger, C., Weiskopf, N. (2016) 'Vascular autorescaling of fMRI (VasA fMRI) improves sensitivity of population studies: A pilot study.' NeuroImage, 124pp. 794-805.

Muthana, M., Kennerley, A., Murphy, E., Hughes, R., Conner, J., Wright, F., Lythgoe, M., Dobson, J., Wild, J., Lewis, C. (2015) 'Use of magnetic resonance targeting to steer ov-loaded cell-based therapies to tumor sites in vivo.' Journal for ImmunoTherapy of Cancer, 3(S2)

Sharp, P.S., Shaw, K., Boorman, L., Harris, S., Kennerley, A.J., Azzouz, M., Berwick, J. (2015) 'Erratum: Comparison of stimulus-evoked cerebral hemodynamics in the awake mouse and under a novel anesthetic regime (Scientific Reports 5 (12621) doi: 10.1038/srep12621).' Scientific Reports, 5

Bain, J., Ruiz-Pérez, L., Kennerley, A.J., Muench, S.P., Thompson, R., Battaglia, G., Staniland, S.S. (2015) 'In situ formation of magnetopolymersomes via electroporation for MRI.' Scientific Reports, 5

Muthana, M., Kennerley, A.J., Hughes, R., Fagnano, E., Richardson, J., Paul, M., Murdoch, C., Wright, F., Payne, C., Lythgoe, M.F., Farrow, N., Dobson, J., Conner, J., Wild, J.M., Lewis, C. (2015) 'Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting.' Nature Communications, 6

Sharp, P.S., Shaw, K., Boorman, L., Harris, S., Kennerley, A.J., Azzouz, M., Berwick, J. (2015) 'Comparison of stimulus-evoked cerebral hemodynamics in the awake mouse and under a novel anesthetic regime.' Scientific Reports, 5

Huber, L., Goense, J., Kennerley, A.J., Trampel, R., Guidi, M., Reimer, E., Ivanov, D., Neef, N., Gauthier, C.J., Turner, R., Möller, H.E. (2015) 'Cortical lamina-dependent blood volume changes in human brain at 7T.' NeuroImage, 107pp. 23-33.

Boorman, L., Harris, S., Bruyns-Haylett, M., Kennerley, A., Zheng, Y., Martin, C., Jones, M., Redgrave, P., Berwick, J. (2015) 'Long-latency reductions in gamma power predict hemodynamic changes that underlie the negative BOLD signal.' Journal of Neuroscience, 35(11) pp. 4641-4656.

Huber, L., Goense, J., Kennerley, A.J., Ivanov, D., Krieger, S.N., Lepsien, J., Trampel, R., Turner, R., Möller, H.E. (2014) 'Investigation of the neurovascular coupling in positive and negative BOLD responses in human brain at 7T.' NeuroImage, 97pp. 349-362.

Harris, S., Ma, H., Zhao, M., Boorman, L., Zheng, Y., Kennerley, A., Bruyns-Haylett, M., Overton, P.G., Berwick, J., Schwartz, T.H. (2014) 'Coupling between gamma-band power and cerebral blood volume during recurrent acute neocortical seizures.' NeuroImage, 97pp. 62-70.

Vidal-Rosas, E.E., Billings, S.A., Zheng, Y., Mayhew, J.E., Johnston, D., Kennerley, A.J., Coca, D. (2014) 'Reduced-order modeling of light transport in tissue for real-time monitoring of brain hemodynamics using diffuse optical tomography.' Journal of Biomedical Optics, 19(2)

Harris, S., Boorman, L., Bruyns-Haylett, M., Kennerley, A., Ma, H., Zhao, M., Overton, P.G., Schwartz, T.H., Berwick, J. (2014) 'Contralateral dissociation between neural activity and cerebral blood volume during recurrent acute focal neocortical seizures.' Epilepsia, 55(9) pp. 1423-1430.

Kennerley, A.J., Boorman, L., Harris, S., Berwick, J. (2014) 'Simultaneous functional magnetic resonance and two-dimensional optical imaging spectroscopy.' Neuromethods, 88pp. 3-20.

Grant, R.A., Sharp, P.S., Kennerley, A.J., Berwick, J., Grierson, A., Ramesh, T., Prescott, T.J. (2013) 'Abnormalities in whisking behaviour are associated with lesions in brain stem nuclei in a mouse model of amyotrophic lateral sclerosis.' Behavioural Brain Research, 259

Harris, S., Bruyns-Haylett, M., Kennerley, A., Boorman, L., Overton, P.G., Ma, H., Zhao, M., Schwartz, T.H., Berwick, J. (2013) 'The effects of focal epileptic activity on regional sensory-evoked neurovascular coupling and postictal modulation of bilateral sensory processing.' Journal of Cerebral Blood Flow and Metabolism, 33(10) pp. 1595-1604.

Martin, C.J., Kennerley, A.J., Berwick, J., Port, M., Mayhew, J.E.W. (2013) 'Functional MRI in conscious rats using a chronically implanted surface coil.' Journal of Magnetic Resonance Imaging, 38(3) pp. 739-744.

Kazan, S.M., Reynolds, S., Kennerley, A., Wholey, E., Bluff, J.E., Berwick, J., Cunningham, V.J., Paley, M.N., Tozer, G.M. (2013) 'Kinetic modeling of hyperpolarized ¹³C pyruvate metabolism in tumors using a measured arterial input function.' Magnetic Resonance in Medicine, 70(4) pp. 943-953.

Zheng, Y., Luo, J.J., Harris, S., Kennerley, A., Berwick, J., Billings, S.A., Mayhew, J. (2012) 'Balanced excitation and inhibition: Model based analysis of local field potentials.' NeuroImage, 63(1) pp. 81-94.

Kennerley, A.J., Mayhew, J.E., Boorman, L., Zheng, Y., Berwick, J. (2012) 'Is optical imaging spectroscopy a viable measurement technique for the investigation of the negative BOLD phenomenon? A concurrent optical imaging spectroscopy and fMRI study at high field (7T).' NeuroImage, 61(1) pp. 10-20.

Kennerley, A.J., Harris, S., Bruyns-Haylett, M., Boorman, L., Zheng, Y., Jones, M., Berwick, J. (2012) 'Early and late stimulus-evoked cortical hemodynamic responses provide insight into the neurogenic nature of neurovascular coupling.' Journal of Cerebral Blood Flow and Metabolism, 32(3) pp. 468-480.

Devonshire, I.M., Papadakis, N.G., Port, M., Berwick, J., Kennerley, A.J., Mayhew, J.E.W., Overton, P.G. (2012) 'Neurovascular coupling is brain region-dependent.' NeuroImage, 59(3) pp. 1997-2006.

Lawrie, A., Hameed, A.G., Chamberlain, J., Arnold, N., Kennerley, A., Hopkinson, K., Pickworth, J., Kiely, D.G., Crossman, D.C., Francis, S.E. (2011) 'Paigen diet-fed apolipoprotein e knockout mice develop severe pulmonary hypertension in an interleukin-1-Dependent Manner.' American Journal of Pathology, 179(4) pp. 1693-1705.

Mead, R.J., Bennett, E.J., Kennerley, A.J., Sharp, P., Sunyach, C., Kasher, P., Berwick, J., Pettmann, B., Battaglia, G., Azzouz, M., Grierson, A., Shaw, P.J. (2011) 'Optimised and rapid pre-clinical screening in the SOD1 ^G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS).' PLoS ONE, 6(8)

Zheng, Y., Pan, Y., Harris, S., Billings, S., Coca, D., Berwick, J., Jones, M., Kennerley, A., Johnston, D., Martin, C., Devonshire, I.M., Mayhew, J. (2010) 'A dynamic model of neurovascular coupling: Implications for blood vessel dilation and constriction.' NeuroImage, 52(3) pp. 1135-1147.

Boorman, L., Kennerley, A.J., Johnston, D., Jones, M., Zheng, Y., Redgrave, P., Berwick, J. (2010) 'Negative blood oxygen level dependence in the rat: A model for investigating the role of suppression in neurovascular coupling.' Journal of Neuroscience, 30(12) pp. 4285-4294.

Kennerley, A.J., Mayhew, J.E., Redgrave, P., Berwick, J. (2010) 'Vascular Origins of BOLD and CBV fMRI Signals: Statistical Mapping and Histological Sections Compared..' The open neuroimaging journal, 4pp. 1-8.

Bonesi, M., Kennerley, A.J., Meglinski, I., Matcher, S. (2009) 'Application of doppler optical coherence tomography in rheological studies: Blood flow and vessels mechanical properties evaluation.' Journal of Innovative Optical Health Sciences, 2(4) pp. 431-440.

Kennerley, A.J., Berwick, J., Martindale, J., Johnston, D., Zheng, Y., Mayhew, J.E. (2009) 'Refinement of optical imaging spectroscopy algorithms using concurrent BOLD and CBV fMRI.' NeuroImage, 47(4) pp. 1608-1619.

Berwick, J., Johnston, D., Jones, M., Martindale, J., Martin, C., Kennerley, A.J., Redgrave, P., Mayhew, J.E.W. (2008) 'Fine detail of neurovascular coupling revealed by spatiotemporal analysis of the hemodynamic response to single whisker stimulation in rat barrel cortex.' Journal of Neurophysiology, 99(2) pp. 787-798.

Martindale, J., Kennerley, A.J., Johnston, D., Zheng, Y., Mayhew, J.E. (2008) 'Theory and generalization of Monte Carlo models of the BOLD signal source.' Magnetic Resonance in Medicine, 59(3) pp. 607-618.

Berwick, J., Devonshire, I.M., Martindale, A.J., Johnston, D., Zheng, Y., Kennerley, A.J., Overton, P.G., Mayhew, J.E.W. (2005) 'Cocaine administration produces a protracted decoupling of neural and haemodynamic responses to intense sensory stimuli.' Neuroscience, 132(2) pp. 361-374.

Kennerley, A.J., Berwick, J., Martindale, J., Johnston, D., Papadakis, N., Mayhew, J.E. (2005) 'Concurrent fMRI and optical measures for the investigation of the hemodynamic response function.' Magnetic Resonance in Medicine, 54(2) pp. 354-365.

Bain, J., Staniland, S., Kennerley, A. (2015) 'Biomimetic synthesis of magnetosomes for MRI application.'

Vidal-Rosas, E.E., Billings, S.A., Zheng, Y., Mayhew, J.E.W., Johnston, D., Kennerly, A., Coca, D. (2011) 'Real-time Diffuse Optical Tomography using reduced-order light propagation models.' pp. 378-385.

Mayhew, J., Berwick, J., Kennerley, A., Martindale, J., Papadakis, N., Zheng, Y. (2004) 'Concurrent optical imaging spectroscopy, laser Doppler flowmetry and magnetic resonance imaging in the investigation of the relative intra and extra vascular contributions to the BOLD signal.'